The smart Trick of ceesdekker That No One is Discussing
The smart Trick of ceesdekker That No One is Discussing
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Nanotechnology features An array of possibilities to contribute to biology. Listed here I will current illustrations wherever nanofabrication – a chance to make confined buildings with Proportions at will – is made use of to look at the biophysics of one molecules and cells. I will current some examples from our lab:
Our team scientific tests bacterial cell division and it is aiming to constitute a ‘base up biology’ in synthetic cells that can autonomously divide. Our main desire lies in cell division, chromatin construction, and spatial control.
Round the identical time, the team of Paul McEuen, who was then dependent on the University of California, Berkeley, confirmed comparable success on ropes of bundled nanotubes. Depending on the wrapping angle, nanotubes can are available metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard College independently confirmed applying scanning tunnelling spectroscopy experiments.
Deposition and atomic drive microscopy of personal phthalocyanine polymers between nanofabricated electrodes
2015, discovery that condensin is actually a extremely adaptable protein construction; and initial detection of DNA knots applying nanopores
The coiled-coil of your human Rad50 DNA mend protein consists of specific segments of greater versatility
You are a Christian. If you could make this type of synthetic mobile, would you be a single stage nearer to God, or would the function of God have diminished to some degree once again?
Move-driven rotary motors including windmills and drinking water wheels travel functional processes in human society. Though samples of these rotary motors also feature prominently in cell biology, their synthetic construction on the nanoscale has remained tough. Below we display flow-driven rotary motion of a self-organized DNA nanostructure that's docked onto a nanopore in a thin strong-state membrane. An elastic DNA bundle self-assembles into a chiral conformation upon phoretic docking onto the solid-state nanopore, and subsequently shows a sustained unidirectional rotary movement of up to twenty rev s−one.
In 1993, being a youthful and eager associate professor at Delft University of Know-how, I'd at first centered the investigate efforts of my group on measuring the electrical conductance of an individual conducting-polymer molecule. In just two years, we had designed a tool wherein an individual wire of the phthalocyaninepolysiloxane polymer was related concerning two closely spaced metal nanoelectrodes.
But carbon nanotubes have remained a study subject of significant curiosity to numerous. Certainly, the outlook on utilizing carbon nanotubes to build practical devices, in areas which include radio-frequency electronics, electronic electronics and flexible electronics, remains vibrant.
Example (four) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is proven in grey, the rim of your pore is highlighted in purple, as well as a 3D rendering from the movement with the DNA rod is shown.
Cees cees dekker Dekker is Distinguished College Professor at TU Delft. Experienced for a physicist, he pioneered nanotechnology with quite a few discoveries on carbon nanotubes from the nineteen nineties. Due to the fact 2000, he moved to one-molecule biophysics and nanobiology. His latest investigation concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, especially SMC motor protein; and (iii) creating a residing synthetic cell from lifeless molecules. Dekker can be an elected member of the KNAW and fellow into the APS as well as IOP.
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij satisfied enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever design in 2005. (nl)